GlenResearch 10-1001說(shuō)明書

發(fā)布時(shí)間：2018/8/15

點(diǎn)擊次數(shù)：415

美國(guó)GRC公司：Glen Research Corp 創(chuàng)建于1987年，專注于為DNA和RNA寡核苷酸的化學(xué)合成，修飾，標(biāo)記和純化提供zui廣泛的亞磷酰胺和固體支持物，現(xiàn)已有近三十年的歷史，在低聚核苷酸及修飾、改性領(lǐng)域一直處于地位。

結(jié)構(gòu)研究

以下產(chǎn)品用于研究當(dāng)關(guān)鍵結(jié)構(gòu)元件改變時(shí)對(duì)寡核苷酸活性的影響。7-脫氮嘌呤單體缺乏對(duì)氫鍵合至關(guān)重要的基團(tuán)。7-Deaza-8-aza-A和7-deaza-8-aza-G（PPG）單體是A和G的異構(gòu)體，并且具有相似的電子密度。它們?cè)诠押塑账嶂械拇嬖谙鄬?duì)于A和G略微穩(wěn)定。與G不同，PPG不會(huì)導(dǎo)致聚集，并且可以容易地制備和分離富含G的寡核苷酸。在5'-末端具有PPG的5'-熒光素寡核苷酸比等同的G寡核苷酸淬滅得少得多。作為胸苷的嘌呤類似物，7-脫氮-2'-脫氧黃嘌呤核苷（7-deaza-dX）有望對(duì)三鏈體的DNA結(jié)構(gòu)產(chǎn)生有趣的影響。7-Deaza-dX還與2,4-二氨基嘧啶核苷類似物形成非標(biāo)準(zhǔn)堿基對(duì)。標(biāo)準(zhǔn)核堿基具有未共享的電子對(duì)，其突出到雙鏈DNA的小溝中。與DNA，聚合酶，逆轉(zhuǎn)錄酶，限制酶等相互作用的酶可以使用氫鍵供體基團(tuán)與小溝中的氫鍵受體接觸。3-Deaza-2'-deoxyadenosine非常有趣，因?yàn)樗３至顺Ｒ?guī)Watson-Crick氫與T鍵合的能力，但缺乏通常由N3提供的3-位的電子對(duì)。

GlenResearch 目錄號(hào)：10-1001-xx

7-Deaza-dA-CE Phosphoramidite
描述：7- Deaza -dA-CE亞磷酰胺

5'-二甲氧基三苯甲基-N-苯甲酰基-7-脫氮-2'-脫氧腺苷，3' - [（2-氰基乙基） - （N，N-二異丙基）] - 亞磷酰胺

分子式：C _4 8 H _5 3 N ₆ O ₇ P.

MW：856.96

FW：312.22

稀釋劑：無(wú)水乙腈

耦合：合成器制造商推薦的標(biāo)準(zhǔn)方法無(wú)需更改。

去保護(hù)：合成器制造商推薦的標(biāo)準(zhǔn)方法無(wú)需更改。

儲(chǔ)存：冷藏，高2-8°C，干燥

溶液中的穩(wěn)定性：類似于dA，C，G，T-CE亞磷酰胺

10-1001-95

50µm

10-1001-90

100µm

10-1001-02

0.25g

EXTINCTION DATA

Item	Nucleoside	λMax-1	Emax-1	λMax-2	Emax-2	E260
		(nm)	(ml/µmole)	nm	(ml/µmole)	(ml/µmole)
10-1001	7-deaza-dA	270	11.3			9.4

DILUTION/COUPLING DATA

下表顯示了包裝尺寸數(shù)據(jù)，以及基于正常灌注程序的溶液，稀釋液和近似偶聯(lián)。請(qǐng)與各種合成器鏈接以獲取更詳細(xì)的使用信息。

ABI 392/394
Cat.No.	Pack Size	Grams/ Pack	0.1M Dil. (mL)	LV40	LV200	40nm	0.2µm	1µm	10µm
Cat.No.	Pack Size	Grams/ Pack	0.1M Dil. (mL)	Approximate Number of Additions
10-1001-02	0.25grams	.25grams	2.92	84	50.4	31.5	22.91	16.8	4.2
10-1001-90	100µmoles	.086grams	1	20	12	7.5	5.45	4	1
10-1001-95	50µmoles	.043grams	.5	3.33	2	1.25	.91	.67	.17
Expedite
Cat.No.	Pack Size	Grams/ Pack	Dilution (mL)	Molarity	50nm	0.2µm	1µm	15µm
Cat.No.	Pack Size	Grams/ Pack	Dilution (mL)	Approximate Number of Additions
10-1001-02	0.25grams	.25grams	4.35	.07	80.6	50.38	36.64	5.04
10-1001-90	100µmoles	.086grams	1.5	.07	23.6	14.75	10.73	1.48
10-1001-95	50µmoles	.043grams	.75	.07	8.6	5.38	3.91	.54

貨號(hào)	品名	規(guī)格	目錄價(jià)	品牌
10-0001-02	dA-5'-CE Phosphoramidite	0.25grams	1275	glen research
10-0001-05	dA-5'-CE Phosphoramidite	0.5grams	2550	glen research
10-0001-10	dA-5'-CE Phosphoramidite	1.0gram	5100	glen research
10-0101-02	dC-5'-CE Phosphoramidite	0.25grams	1275	glen research
10-0101-05	dC-5'-CE Phosphoramidite	0.5grams	2550	glen research
10-0101-10	dC-5'-CE Phosphoramidite	1.0gram	5100	glen research
10-0301-02	dT-5'-CE Phosphoramidite	0.25grams	1275	glen research
10-0301-05	dT-5'-CE Phosphoramidite	0.5grams	2550	glen research
10-0301-10	dT-5'-CE Phosphoramidite	1.0gram	5100	glen research
10-1000-02	dA-CE Phosphoramidite	0.25grams	212.5	glen research
10-1000-02M	dA-CE Phosphoramidite	0.25grams	212.5	glen research
10-1000-05	dA-CE Phosphoramidite	0.5grams	425	glen research
10-1000-05M	dA-CE Phosphoramidite	0.5grams	425	glen research
10-1000-10	dA-CE Phosphoramidite	1.0gram	850	glen research
10-1000-10M	dA-CE Phosphoramidite	1.0gram	850	glen research
10-1000-1C	dA-CE Phosphoramidite	1.0gram	850	glen research
10-1000-1S	dA-CE Phosphoramidite	10.0grams	8500	glen research
10-1000-20	dA-CE Phosphoramidite	2.0grams	1700	glen research
10-1000-2C	dA-CE Phosphoramidite	2.0grams	1700	glen research
10-1000-40	dA-CE Phosphoramidite	4.0grams	3400	glen research
10-1000-50	dA-CE Phosphoramidite	5.0grams	4250	glen research
10-1000-5S	dA-CE Phosphoramidite	5.0grams	4250	glen research
10-1000-C2	dA-CE Phosphoramidite	0.25grams	212.5	glen research
10-1000-C5	dA-CE Phosphoramidite	0.5grams	425	glen research
10-1001-02	7-Deaza-dA-CE Phosphoramidite	0.25grams	16575	glen research
10-1001-90	7-Deaza-dA-CE Phosphoramidite	100µmoles	6035	glen research
10-1001-95	7-Deaza-dA-CE Phosphoramidite	50µmoles	3017.5	glen research
10-1002-02	dA+dG-CE Phosphoramidite	0.25grams	680	glen research
10-1003-02	N6-Me-dA-CE Phosphoramidite	0.25grams	8415	glen research
10-1003-90	N6-Me-dA-CE Phosphoramidite	100µmoles	2762.5	glen research
10-1004-02	3'-dA-CE Phosphoramidite	0.25grams	16575	glen research
10-1004-90	3'-dA-CE Phosphoramidite	100µmoles	6035	glen research
10-1004-95	3'-dA-CE Phosphoramidite	50µmoles	3017.5	glen research
10-1006-02	Etheno-dA-CE Phosphoramidite	0.25grams	4335	glen research
10-1006-90	Etheno-dA-CE Phosphoramidite	100µmoles	1785	glen research
10-1007-02	8-Br-dA-CE Phosphoramidite	0.25grams	5015	glen research
10-1007-90	8-Br-dA-CE Phosphoramidite	100µmoles	1955	glen research
10-1008-02	8-oxo-dA-CE Phosphoramidite	0.25grams	6035	glen research
10-1008-90	8-oxo-dA-CE Phosphoramidite	100µmoles	2295	glen research
10-1010-02	dC-CE Phosphoramidite	0.25grams	212.5	glen research
10-1010-02M	dC-CE Phosphoramidite	0.25grams	212.5	glen research
10-1010-05	dC-CE Phosphoramidite	0.5grams	425	glen research
10-1010-05M	dC-CE Phosphoramidite	0.5grams	425	glen research
10-1010-10	dC-CE Phosphoramidite	1.0gram	850	glen research
10-1010-10M	dC-CE Phosphoramidite	1.0gram	850	glen research
10-1010-1C	dC-CE Phosphoramidite	1.0gram	850	glen research
10-1010-1S	dC-CE Phosphoramidite	10.0grams	8500	glen research
10-1010-20	dC-CE Phosphoramidite	2.0grams	1700	glen research
10-1010-2C	dC-CE Phosphoramidite	2.0grams	1700	glen research
10-1010-40	dC-CE Phosphoramidite	4.0grams	3400	glen research
10-1010-50	dC-CE Phosphoramidite	5.0grams	4250	glen research
10-1010-5S	dC-CE Phosphoramidite	5.0grams	4250	glen research
10-1010-C2	dC-CE Phosphoramidite	0.25grams	212.5	glen research
10-1010-C5	dC-CE Phosphoramidite	0.5grams	425	glen research
10-1013-02	dC+dT-CE Phosphoramidite	0.25grams	680	glen research
10-1014-02	pdC-CE Phosphoramidite	0.25grams	4165	glen research
10-1014-05	pdC-CE Phosphoramidite	0.5grams	8330	glen research
10-1014-90	pdC-CE Phosphoramidite	100µmoles	1445	glen research
10-1015-02	Ac-dC-CE Phosphoramidite	0.25grams	212.5	glen research
10-1015-02M	Ac-dC-CE Phosphoramidite	0.25grams	212.5	glen research
10-1015-05	Ac-dC-CE Phosphoramidite	0.5grams	425	glen research
10-1015-05M	Ac-dC-CE Phosphoramidite	0.5grams	425	glen research
10-1015-10	Ac-dC-CE Phosphoramidite	1.0gram	850	glen research
10-1015-10M	Ac-dC-CE Phosphoramidite	1.0gram	850	glen research
10-1015-1C	Ac-dC-CE Phosphoramidite	1.0gram	850	glen research
10-1015-1S	Ac-dC-CE Phosphoramidite	10.0grams	8500	glen research
10-1015-20	Ac-dC-CE Phosphoramidite	2.0grams	1700	glen research
10-1015-2C	Ac-dC-CE Phosphoramidite	2.0grams	1700	glen research
10-1015-40	Ac-dC-CE Phosphoramidite	4.0grams	3400	glen research
10-1015-50	Ac-dC-CE Phosphoramidite	5.0grams	4250	glen research
10-1015-5S	Ac-dC-CE Phosphoramidite	5.0grams	4250	glen research
10-1015-C2	Ac-dC-CE Phosphoramidite	0.25grams	212.5	glen research
10-1015-C5	Ac-dC-CE Phosphoramidite	0.5grams	425	glen research
10-1016-02	TMP-F-dU-CE Phosphoramidite	0.25grams	8415	glen research
10-1016-90	TMP-F-dU-CE Phosphoramidite	100µmoles	3315	glen research
10-1017-02	Pyrrolo-dC-CE Phosphoramidite	0.25grams	11475	glen research
10-1017-90	Pyrrolo-dC-CE Phosphoramidite	100µmoles	3740	glen research
10-1017-95	Pyrrolo-dC-CE Phosphoramidite	50µmoles	1870	glen research
10-1018-02	5-Me-dC Brancher Phosphoramidite	0.25grams	8585	glen research
10-1018-90	5-Me-dC Brancher Phosphoramidite	100µmoles	3485	glen research
10-1019-02	Amino-Modifier C6 dC	0.25grams	7650	glen research
10-1019-90	Amino-Modifier C6 dC	100µmoles	3825	glen research
10-1020-02	dG-CE Phosphoramidite	0.25grams	212.5	glen research
10-1020-02M	dG-CE Phosphoramidite	0.25grams	212.5	glen research
10-1020-05	dG-CE Phosphoramidite	0.5grams	425	glen research
10-1020-05M	dG-CE Phosphoramidite	0.5grams	425	glen research
10-1020-10	dG-CE Phosphoramidite	1.0gram	850	glen research
10-1020-10M	dG-CE Phosphoramidite	1.0gram	850	glen research
10-1020-1C	dG-CE Phosphoramidite	1.0gram	850	glen research
10-1020-1S	dG-CE Phosphoramidite	10.0grams	8500	glen research
10-1020-20	dG-CE Phosphoramidite	2.0grams	1700	glen research
10-1020-2C	dG-CE Phosphoramidite	2.0grams	1700	glen research
10-1020-40	dG-CE Phosphoramidite	4.0grams	3400	glen research
10-1020-50	dG-CE Phosphoramidite	5.0grams	4250	glen research
10-1020-5S	dG-CE Phosphoramidite	5.0grams	4250	glen research
10-1020-C2	dG-CE Phosphoramidite	0.25grams	212.5	glen research
10-1020-C5	dG-CE Phosphoramidite	0.5grams	425	glen research
10-1021-02	7-deaza-dG-CE Phosphoramidite	0.25grams	16575	glen research
10-1021-90	7-deaza-dG-CE Phosphoramidite	100µmoles	6035	glen research
10-1021-95	7-deaza-dG-CE Phosphoramidite	50µmoles	3017.5	glen research
10-1023	dA+dC+dG+dT-CE Phosphoramidite Mix	1.0gram	680	glen research
10-1027-02	8-Br-dG-CE Phosphoramidite	0.25grams	4335	glen research
10-1027-90	8-Br-dG-CE Phosphoramidite	100µmoles	1785	glen research
10-1028-02	8-oxo-dG-CE Phosphoramidite	0.25grams	16575	glen research
10-1028-90	8-oxo-dG-CE Phosphoramidite	100µmoles	6035	glen research
10-1028-95	8-oxo-dG-CE Phosphoramidite	50µmoles	3017.5	glen research
10-1029-02	dmf-dG-CE Phosphoramidite	0.25grams	212.5	glen research
10-1029-02M	dmf-dG-CE Phosphoramidite	0.25grams	212.5	glen research
10-1029-05	dmf-dG-CE Phosphoramidite	0.5grams	425	glen research
10-1029-05M	dmf-dG-CE Phosphoramidite	0.5grams	425	glen research
10-1029-10	dmf-dG-CE Phosphoramidite	1.0gram	850	glen research
10-1029-10M	dmf-dG-CE Phosphoramidite	1.0gram	850	glen research
10-1029-1C	dmf-dG-CE Phosphoramidite	1.0gram	850	glen research
10-1029-1S	dmf-dG-CE Phosphoramidite	10.0grams	8500	glen research
10-1029-20	dmf-dG-CE Phosphoramidite	2.0grams	1700	glen research
10-1029-2C	dmf-dG-CE Phosphoramidite	2.0grams	1700	glen research
10-1029-40	dmf-dG-CE Phosphoramidite	4.0grams	3400	glen research
10-1029-50	dmf-dG-CE Phosphoramidite	5.0grams	4250	glen research
10-1029-5S	dmf-dG-CE Phosphoramidite	5.0grams	4250	glen research
10-1029-C2	dmf-dG-CE Phosphoramidite	0.25grams	212.5	glen research
10-1029-C5	dmf-dG-CE Phosphoramidite	0.5grams	425	glen research
10-1030-02	dT-CE Phosphoramidite	0.25grams	212.5	glen research
10-1030-02M	dT-CE Phosphoramidite	0.25grams	212.5	glen research
10-1030-05	dT-CE Phosphoramidite	0.5grams	425	glen research
10-1030-05M	dT-CE Phosphoramidite	0.5grams	425	glen research
10-1030-10	dT-CE Phosphoramidite	1.0gram	850	glen research
10-1030-10M	dT-CE Phosphoramidite	1.0gram	850	glen research
10-1030-1C	dT-CE Phosphoramidite	1.0gram	850	glen research
10-1030-1S	dT-CE Phosphoramidite	10.0grams	8500	glen research
10-1030-20	dT-CE Phosphoramidite	2.0grams	1700	glen research
10-1030-2C	dT-CE Phosphoramidite	2.0grams	1700	glen research
10-1030-40	dT-CE Phosphoramidite	4.0grams	3400	glen research
10-1030-50	dT-CE Phosphoramidite	5.0grams	4250	glen research
10-1030-5S	dT-CE Phosphoramidite	5.0grams	4250	glen research
10-1030-C2	dT-CE Phosphoramidite	0.25grams	212.5	glen research
10-1030-C5	dT-CE Phosphoramidite	0.5grams	425	glen research
10-1031-02	5'-OMe-dT-CE Phosphoramidite	0.25grams	6035	glen research
10-1031-90	5'-OMe-dT-CE Phosphoramidite	100µmoles	2295	glen research
10-1032-02	O4-Me-dT-CE Phosphoramidite	0.25grams	6035	glen research
10-1032-90	O4-Me-dT-CE Phosphoramidite	100µmoles	2295	glen research
10-1034-02	4-Thio-dT-CE Phosphoramidite	0.25grams	11475	glen research
10-1034-90	4-Thio-dT-CE Phosphoramidite	100µmoles	5015	glen research
10-1034-95	4-Thio-dT-CE Phosphoramidite	50µmoles	2805	glen research
10-1035-02	Carboxy-dT	0.25grams	6120	glen research
10-1035-90	Carboxy-dT	100µmoles	3060	glen research
10-1036-02	2-Thio-dT-CE Phosphoramidite	0.25grams	11475	glen research
10-1036-90	2-Thio-dT-CE Phosphoramidite	100µmoles	5015	glen research
10-1036-95	2-Thio-dT-CE Phosphoramidite	50µmoles	2805	glen research
10-1037-02	Amino-Modifier C2 dT	0.25grams	6120	glen research
10-1037-05	Amino-Modifier C2 dT	0.5grams	12240	glen research
10-1037-90	Amino-Modifier C2 dT	100µmoles	3060	glen research
10-1038-02	Biotin-dT	0.25grams	10625	glen research
10-1038-90	Biotin-dT	100µmoles	5525	glen research
10-1038-95	Biotin-dT	50µmoles	2847.5	glen research
10-1039-02	Amino-Modifier C6 dT	0.25grams	6120	glen research
10-1039-05	Amino-Modifier C6 dT	0.5grams	12240	glen research
10-1039-90	Amino-Modifier C6 dT	100µmoles	3060	glen research
10-1040-02	dI-CE Phosphoramidite	0.25grams	2040	glen research
10-1040-90	dI-CE Phosphoramidite	100µmoles	850	glen research
10-1041-02	2'-DeoxyNebularine-CE Phosphoramidite (Purine)	0.25grams	4335	glen research
10-1041-90	2'-DeoxyNebularine-CE Phosphoramidite (Purine)	100µmoles	1785	glen research
10-1042-02	O6-Phenyl-dI-CE Phosphoramidite	0.25grams	6035	glen research
10-1042-90	O6-Phenyl-dI-CE Phosphoramidite	100µmoles	2295	glen research
10-1044-02	5-Nitroindole-CE Phosphoramidite	0.25grams	5525	glen research
10-1044-90	5-Nitroindole-CE Phosphoramidite	100µmoles	2125	glen research
10-1046-02	2-Aminopurine-CE Phosphoramidite	0.25grams	6035	glen research
10-1046-90	2-Aminopurine-CE Phosphoramidite	100µmoles	2295	glen research
10-1047-02	dP-CE Phosphoramidite	0.25grams	10115	glen research
10-1047-90	dP-CE Phosphoramidite	100µmoles	3315	glen research
10-1048-02	dK-CE Phosphoramidite	0.25grams	10115	glen research
10-1048-90	dK-CE Phosphoramidite	100µmoles	3315	glen research
10-1049-02	dP+dK-CE Phosphoramidite	0.25grams	10115	glen research
10-1049-90	dP+dK-CE Phosphoramidite	100µmoles	3315	glen research
10-1050-02	dU-CE Phosphoramidite	0.25grams	1700	glen research
10-1050-90	dU-CE Phosphoramidite	100µmoles	595	glen research
10-1051-02	O4-Triazolyl-dU-CE Phosphoramidite	0.25grams	6035	glen research
10-1051-90	O4-Triazolyl-dU-CE Phosphoramidite	100µmoles	2295	glen research
10-1052-02	4-Thio-dU-CE Phosphoramidite	0.25grams	11475	glen research
10-1052-90	4-Thio-dU-CE Phosphoramidite	100µmoles	5015	glen research
10-1052-95	4-Thio-dU-CE Phosphoramidite	50µmoles	2805	glen research
10-1053-02	5-OH-dU-CE Phosphoramidite	0.25grams	11475	glen research
10-1053-90	5-OH-dU-CE Phosphoramidite	100µmoles	3825	glen research
10-1054-02	pdU-CE Phosphoramidite	0.25grams	3315	glen research
10-1054-05	pdU-CE Phosphoramidite	0.5grams	6630	glen research
10-1054-90	pdU-CE Phosphoramidite	100µmoles	1105	glen research
10-1055-02	2'-deoxypseudoU-CE Phosphoramidite	0.25grams	16575	glen research
10-1055-90	2'-deoxypseudoU-CE Phosphoramidite	100µmoles	6035	glen research
10-1055-95	2'-deoxypseudoU-CE Phosphoramidite	50µmoles	3017.5	glen research
10-1056-02	Fluorescein-dT Phosphoramidite	0.25grams	11475	glen research

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3：提供加急服務(wù)，貨品一般1-2周到貨。

4：富有競(jìng)爭(zhēng)力的價(jià)格優(yōu)勢(shì)，絕大部分價(jià)格有優(yōu)勢(shì)。

5：多年積累良好的信譽(yù)，大部分客戶提供貨到付款服務(wù)。客戶包括清華、北大、交大、復(fù)旦、中山等100多所高校，ROCHE，阿斯利康、國(guó)藥、fisher等知藥企。

6：我們還是Santa,Advanced Biotechnologies Inc,Athens Research & Technology,bangs,BBInternational,crystalchem,dianova,FD Neurotechnologies,Inc. FormuMax Scientific,Inc, Genebridege, Glycotope Biotechnology GmbH; iduron,Innovative Research of America, Ludger, neuroprobe,omicronbio, Polysciences,prospecbi, QA-BIO,quickzyme,RESEARCH DIETS,INC,sterlitech；sysy,TriLink BioTechnologies,Inc；worthington-biochem,zyagen等幾十家國(guó)外公司授權(quán)代理。

7：我們還是invitrogen,qiagen,MiraiBioam,sigma;neb,roche,merck, rnd,BD, GE,pierce,BioLegend等知*批發(fā)，歡迎合作。

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GlenResearch 10-1001說(shuō)明書

結(jié)構(gòu)研究

GlenResearch 目錄號(hào)：10-1001-xx

7-Deaza-dA-CE Phosphoramidite描述：7- Deaza -dA-CE亞磷酰胺

EXTINCTION DATA

DILUTION/COUPLING DATA

DILUTION/COUPLING DATA

7-Deaza-dA-CE Phosphoramidite
描述：7- Deaza -dA-CE亞磷酰胺